Weeks' paintings are characterized by their grand scale, luminous color palettes, and meticulous attention to architectural detail. His works often depict bustling marketplaces, grand palaces, and religious ceremonies, showcasing the rich cultural tapestry of the regions he visited. One of his great strengths was his ability to capture the interplay of light and shadow, particularly in sun-drenched cityscapes and interior scenes. His highly detailed and immersive compositions transported European and American audiences to far-off lands, embodying the essence of 19th-century Orientalist painting.